Association of interleukin 18 (IL18) polymorphisms with specific IgE levels to mite allergens among asthmatic patients

Association of interleukin 18 (IL18) polymorphisms with specific IgE levels to mite allergens among asthmatic patients.

BACKGROUND Allergy is regarded as a multifactorial condition. Its onset and severity are influenced by both genetic and environmental factors. Identification of genetic factors involved in asthma development and related phenotypes is a major task in understanding the genetic background of asthma. The possible involvement of IL18 polymorphisms in asthma was examined in a Korean asthma cohort. ...

Genome-wide association study identifies variants at the IL18-BCO2 locus associated with interleukin-18 levels.

OBJECTIVE Interleukin-18 (IL-18) is a proinflammatory cytokine involved in the processes of innate and acquired immunities and associated with cardiovascular disease and type 2 diabetes. We sought to identify the common genetic variants associated with IL-18 levels. METHODS AND RESULTS We performed a 2-stage genome-wide association study among women of European ancestry from the Nurses' Healt...

Specific IgE Assay for Respiratory Allergens in Patients with Atopy in Ahvaz, Iran

Association of Interleukin-4 and IgE Levels with LDL Oxidation in Atherosclerosis

Background: Atherosclerosis is an inflammatory and multifactorial disease, with a high prevalence rate in Pakistan. Objective: To find a relation between serum IL-4 and IgE levels with oxidized LDL in atherosclerosis. Methods: In this observational, cross sectional study 99 male patients, between forty and sixty years of age, with a history of ischemic heart disease (IHD) and established athero...

Specific IgE to Common Food Allergens in Children with Atopic Dermatitis

Background: Atopic dermatitis is a major public health problem, often starting in early childhood and sometimes followed by other allergic diseases. Although hypersensitivity to foods is assumed to play an essential role in the development of atopic dermatitis in some patients, little is known about common food allergens in Iranian children with atopic dermatitis. Objectives: This study was des...